(3) IMMUNE RESPONSES WITH AGEING
نویسندگان
چکیده
منابع مشابه
Successful immunosenescence and the remodelling of immune responses with ageing.
In recent decades, major theoretical and technological advances have been achieved in the field of immunology. These have allowed the scientific community to analyse the immune system in a much more sophisticated manner than was possible even 20 years ago. Moreover, great theoretical changes have also occurred in gerontology-in particular, the hypothesis has been put forward that ageing and dis...
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Decreases in immune responsiveness with age are thought to contribute to the increased incidence and severity of infectious disease among the elderly. Several interventions, including exercise, have been proposed to restore immune function in older populations. The findings from some, but not all studies, support the possibility that exercise may attenuate immunosenescence. In recent years, the...
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It is widely accepted that cell-mediated immune functions decline with age, rendering an individual more susceptible to infection and possibly cancer, as well as to age-associated autoimmune diseases. The exact causes of T-cell functional decline are not known. One possible cause could be the development of defects in the transduction of mitogenic signals following TCR stimulation. This T-cell ...
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The pathology of many of the world's most important infectious diseases is caused by the immune response. Additionally age-related disease is often attributed to inflammatory responses. Consequently a reduction in infections and hence inflammation early in life has been hypothesized to explain the rise in lifespan in industrialized societies. Here we demonstrate experimentally for the first tim...
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ژورنال
عنوان ژورنال: Nihon Naika Gakkai Zasshi
سال: 1970
ISSN: 0021-5384,1883-2083
DOI: 10.2169/naika.59.1062